College of Medicine

Research Area(s)

  • Irreversible Electroporation (NanoKnife): Clinical program and research
  • Pancreatic Cancer
  • Immuno-oncology
  • Kidney Transplantation
  • Research in machine cold perfusion preservation of kidneys for transplant
  • Organ donor awareness
  • Medical Education
  • Tumor Ablation Technologies
  • Biomedical Engineering

About

Current Appointments:

  • Associate Professor, Department of Surgery, College of Medicine, University of Saskatchewan (with tenure)
  • Associate member, Department of Pharmacy and Nutrition, University of Saskatchewan
  • Associate member, Department of Biomedical Engineering, University of Saskatchewan

Education:

  • Bachelor of Science, University of Alberta, Biochemistry / Biostatistics.
  • Doctor of Medicine, University of Alberta, with Distinction and Honors in Research.
  • Masters of Science in Experimental Surgery, Universities of Alberta and Manitoba, Thesis: Preoperative treatments in cirrhotic liver resection.
  • Fellow of the Royal College of Surgeons of Canada (FRCSC), University of Alberta
  • Fellowship in Liver and Kidney Transplantation (ASTS accredited) and Hepatobiliary Surgery, University of Western Ontario

Awards:

  • 2023 Department of Surgery Golden Scalpel Award for Pre-clerkship Education
  • 2022 Logan Boulet Humanitarian of the Year Award, Angel's Legacy Foundation (awarded May 2023)
  • 2023 Student Medical Society of Saskatchewan Pre-clerkship Teacher of the Year
  • 2021 2nd Place Podium Presentation, Department of Surgery Faculty Research Day: A Research Day Project about Research Day Projects (May)
  • 2011 PAIRS Resident Teacher of the Year for 2011, Professional Association of Interns and Residents of Saskatchewan
  • 2008 Saskatoon Physician Teacher of the Year, Medicine Class of 2008
  • 2006 Haig Undergraduate Surgery Teaching Award, Department of Surgery

Selected Publications

  • Tait C, Moser M, McKinney V, Kappel J, Henry B. Collective intelligence to solve complex health challenges facing Indigenous peoples: organ donation and transplantation. Accepted to AlterNative Journal.
  • Baig Z, Sarwar Z, Verdiales C, Moser M (2022). The role of collaboration and mentorship in the publication of surgical resident research. Can Med Ed J. 2023; 14(3); https://doi.org/10.36834/cmej.73692.
  • McInnes AD, Moser M. Chen, X. (2023). Preparation and Use of Decellularized Extracellular Matrix for Tissue Engineering. Journal of Functional Biomaterials, 13: 240-258.
  • Wall, C., Ahmed, S., Kabir, R., Lim, HJ., Iqbal, M., Chalchal, H., Domes, T., Beck, G., Luo, Y., Ogaick, M., Shaw, J. & Moser M. (2022). Early Single-Center Experience with Irreversible Electroporation for Stage 2, 3, and 4 Pancreatic Adenocarcinomas. Pancreas, 51(8): 976-984. [First Canadian report of IRE used clinically for pancreatic cancer; the results looked very similar to those reported by the larger centres that had reported in the past (Louisville and Miami, USA and London, UK) in terms of survival]
  • McNair ED, Bezaire J, Moser M, Mondal P, Conacher J, Franczak A, Sawicki G, Reid D, Khani-Hanjani A. The Association of Matrix Metalloproteinases with Acute Kidney Injury Following Cardiopulmonary-Bypass-Supported Cardiac Surgery. Can J Kidney Health Dis. 2021 Jul 16;8:20543581211019640. doi: 10.1177/20543581211019640. PMID: 34350005; PMCID: PMC8287351.
  • Ahmed, S., Moser M, Dueck & Zaidi (2022). Systemic Therapy and Its Surgical Implications in Patients with Resectable Liver Colorectal Cancer Metastases. A Report from the Western Canadian Gastrointestinal Cancer Consensus Conference. Current Oncology, 29(3): 1796-1807.
  • Muhammadzai J, Haider K, Moser M, Chalchal H, Shaw J, Gardiner D, Dueck DA, Ahmed O, Brunet B, Iqbal M, Luo Y, Beck G, Zaidi A, Ahmed S. Early discontinuation of adjuvant chemotherapy in patients with early-stage pancreatic cancer correlates with inferior survival: A multicenter population-based cohort study. PLoS One. 2022 Feb 2;17(2): e0263250. doi: 10.1371/journal.pone.0263250. PMID: 35108323; PMCID: PMC8809602.
  • Zaidi, A., Ahmed, S., Brunet, B., Davies, J., Doll, C., Dueck, D., Gordon, V., Hebbard, P., Kim, C., Le, D., Ying, R., Lim, H., Liu, D., Mulder, K., Park, J., Renouf, D., Schellenberg, D., Wong, R, Moser M. (2021). Report from the Western Canadian Gastrointestinal Cancer Consensus Conference Virtual Education Series-Transition from Local to System Therapy and Optimal Sequencing of Systemic Therapy for HCC. Curr Oncol 28(6): 4317-4327.
  • Bubis LD, Behman R, Roke R, Serrano PE, Khalil JA, Coburn NG, Law CH, Bertens K, Martel G, Hallet J, Marcaccio M, Balaa F, Quan D, Gallinger S, Nanji S, Leslie K, Tandan V, Luo Y, Beck G, Skaro A, Dath D, Moser M, Karanicolas PJ; HPB CONCEPT team. PATCH-DP: a single-arm phase II trial of intra-operative application of HEMOPATCH™ to the pancreatic stump to prevent post-operative pancreatic fistula following distal pancreatectomy. HPB (Oxford). 2022 Jan;24(1):72-78. doi: 10.1016/j.hpb.2021.05.007. Epub 2021 Jun 9. PMID: 34176743.
  • Zaidi A, Chandna N, Narasimhan G, Moser M, Haider K, Chalchal H, Shaw J, Ahmed S. Second-line Chemotherapy Prolongs Survival in Real World Patients with Advanced Biliary Tract and Gallbladder Cancers: A Multicenter Retrospective Population-based Cohort Study. Am J Clin Oncol. 2021 Mar 1;44(3):93-98. doi: 10.1097/COC.0000000000000789. PMID: 33350678.
  • Fang Z, Mao H, Moser M, Zhang W, Qian Z, Zhang B. Irreversible Electroporation Enhanced by Radiofrequency Ablation: An In Vitro and Computational Study in a 3D Liver Tumor Model. Ann Biomed Eng. 2021 Sep;49(9):2126-2138. doi: 10.1007/s10439-021-02734-x. Epub 2021 Feb 16. PMID: 33594637.
  • Moser M, Schmid S, Sawicka K, Banerjee T, McNair E, Sawicka J, Bil-Lula I, Sawicki G. Pre-arrest doxycycline protects donation after circulatory death kidneys. Sci Rep. 2020 Dec 17;10(1):22272. doi: 10.1038/s41598-020-79440-6. PMID: 33335249; PMCID: PMC7746739.
  • Templeton S, Moser M, Wall C, Shaw J, Chalchal H, Luo Y, Zaidi A, Ahmed S. Outcomes of Patients with Borderline Resectable Pancreatic Cancer Treated with Combination Chemotherapy. J Gastrointest Cancer. 2021 Jun;52(2):529-535. doi: 10.1007/s12029-020-00417-9. PMID: 32440849. [Co-investigator, Surgical Lead, Impact Factor 2.6]
  • Conlon L, Baig Z, Moser M. What information are patients receiving from the Internet about the operative and nonoperative management of acute appendicitis? Dig Surg 2020; 37(6): 480-487.
  • Moser M, Schmid S, Sawicka K, Banerjee T, McNair E, Sawicka J, Bil-Lula I, Sawicki G. Pre-arrest doxycycline protects donation after circulatory death kidneys. Sci Rep 2020 Dec 17; 10(1): 222-227.
  • Moser M, Sawicka K, Sawicka J, Franczak A, Cohen A, Bil-Lula I, Sawicki G. Protection of the transplant kidney during cold perfusion with doxycycline: proteomic analysis in a rat model. Proteome Sci. 2020 Apr 20;18:3. doi: 10.1186/s12953-020-00159-3. PMID: 32336955; PMCID: PMC7171734.
  • Papneja, N., Zaidi, A., Chalchal, H., Moser M, Ahmed, S. (2019). Papneja N, Zaidi A, Chalchal H, et al. Comparisons of Outcomes of Real-World Patients with Advanced Pancreatic Cancer Treated with FOLFIRINOX Versus Gemcitabine and Nab-Paclitaxel: A Population-Based Cohort Study. Pancreas. 2019;48(7):920–926. doi:10.1097/MPA.0000000000001340. Pancreas, 48(7): 920-926.
  • Sawicka K, Hassan N, Dumaine C, Budd A, Wall C, Banerjee T, Lim HJ, Mondal P, Barton J, Moser M. Direction of the Biopsy Needle in Ultrasound-Guided Renal Biopsy Impacts Specimen Adequacy and Risk of Bleeding. Can Assoc Radiol J. 2019 Nov;70(4):361-366. doi: 10.1016/j.carj.2018.11.006. Epub 2019 Mar 27. PMID: 30928202.
  • Xu A, Zhang L, Yuan J, Babikr F, Freywald A, Chibbar R, Moser M, Zhang W, Zhang B, Fu Z, Xiang J. TLR9 agonist enhances radiofrequency ablation-induced CTL responses, leading to the potent inhibition of primary tumor growth and lung metastasis. Cell Mol Immunol. 2019 Oct;16(10):820-832. doi: 10.1038/s41423-018-0184-y. Epub 2018 Nov 22. PMID: 30467420; PMCID: PMC6804546.
  • Papneja N, Zaidi A, Chalchal H, Moser M, Tan K, Olson C, Haider K, Shaw J, Ahmed S. Comparisons of Outcomes of Real-World Patients With Advanced Pancreatic Cancer Treated With FOLFIRINOX Versus Gemcitabine and Nab-Paclitaxel. Pancreas. 2019 Jun 7.
  • Zhang, B., Yang, Y., Ding, L., Moser, M. A., Zhang, E. M., & Zhang, W. (2019). Tumor Ablation Enhancement by Combining Radiofrequency Ablation and Irreversible Electroporation: An In Vitro 3D Tumor Study. Annals of biomedical engineering, 47(3), 694-705.
  • Dang, Z., Moser, M. A., Zhang, E., Zhang, W., & Zhang, B. (2019). Design of a novel electrode of radiofrequency ablation for large tumors: In vitro validation and evaluation. Journal of biomechanical engineering, 141(3).
  • Xu A, Zhang L, Yuan J, Babikr F, Freywald A, Chibbar R, Moser M, Zhang W, Zhang B, Fu Z, Xiang J. TLR9 agonist enhances radiofrequency ablation-induced CTL responses, leading to potent inhibition of primary tumor growth and lung metastases. Cellular and Molecular Immunology. 2018 Nov. Epub 2018 Nov.
  • Sawicka K, Hassan N, Budd A, Wall C, Banerjee T, Lim J, Mondal P, Barton J, Moser M. Direction of the biopsy needle in ultrasound-guided renal biopsy impacts specimen adequacy and risk of bleeding. Canadian Association of Radiologists Journal. 2018 Nov. Epub 2019 Mar 27. https://doi.org/10.1016/j.carj.2018.11.006.
  • Yang Y, Ding L, Moser M, Zhang E, Zhang W, Zhang B. Tumor ablation enhancement by combining radiofrequency ablation and irreversible electroporation: An In Vitro 3D tumor study. Annals of Biomedical Engineering. 2018 Sep.
  • Thiessen L, MacDonell S, Wall C, Jacob P, Shoker A, Moser M. Transplant renal vein thrombosis in a recipient with aberrant venous anatomy. CEN Case Reports. 2018 May. Epub 2018 May. https://doi.org/10.1007/s13730-018-0340-3.
  • Yang Y, Moser M, Zhang E, Zhang W, Zhang B. Optimization of electrode configuration and pulse strength in Irreversible Electroporation for large ablation volumes without thermal damage. Journal of Engineering and Science in Medical Diagnostics and Therapy. 2018 May;1(2):1-8.
  • Moser M., Ginther, N., Luo, Y., Beck, G., Ginther, R., Ewen, M., Matsche-Neufeld, R., Shoker, A. & Sawicki, G. (2017). Early experience with hypothermic machine perfusion of living donor kidneys. Transplant International, 30(7): 706-712.
  • Fang J, Moser MAJ, Zhang B, Zhang E, Zhang W. Design of a novel electrode for radiofrequency ablation for large tumors: A finite element study. ASME Journal. 2017 Sep.
  • Zhang B, Moser M, Xiang J, Zhang E, Zhang W. An In Vitro experimental study of the pulse delivery method in irreversible electroporation. J Eng Sci Med Diag Ther. 2017 Sep.
  • Moser M, Sawicka K, Arcand S, O'brien P, Luke P, Beck G, Sawicka J, Cohen A, Sawicki G. Proteomic analysis of perfusate from machine cold perfusion of transplant kidneys: insights into protection from injury. Annals of Transplantation. 2017 Jul.
  • Moser MAJ, Ginther N, Luo Y, Beck G, Ginther R, Ewen M, Matsche-Neufeld R, Shoker A, Sawicki G. Early experience with hypothermic machine perfusion of living donor kidneys. Transplant International. 2017 Jul;30(7):706-712.
  • Zhang, B., Moser, M. A., Zhang, E. M., Luo, Y., & Zhang, W. (2017). A new approach to feedback control of radiofrequency ablation systems for large coagulation zones. International Journal of Hyperthermia, 33(4), 367-377.