Editor’s ChoiceFermentable oligo-, di-, monosaccharides, and polyols (FODMAPs), but not gluten, elicit modest symptoms of irritable bowel syndrome: a double-blind, placebo-controlled, randomized three-way crossover trial
Under a Creative Commons license
open access
Keywords:
diet
fermentation
functional gastrointestinal disorder
polyols
saccharides
irritable bowel syndrome
FODMAPs
gluten
double-blind
crossover trial
Abbreviations used:
A
FODMAPs
B
gluten
C
placebo in blocks of 12
FODMAPs
fermentable oligo-, di-, monosaccharides, and polyols
IBS-C/D/M/U
irritable bowel syndrome-constipation/diarrhea/mixed/unsubtyped
IBS-SSS
irritable bowel syndrome-severity scoring system
ITT
intention-to-treat
PP
per-protocol
SF-36v2
Short Form 36 version 2
QoL
quality of life.
Cited by (0)
The study was funded by Formas (grant number: 2016-00314) and the Swedish Research Council (grant number: 2017-05840). The funders had no part in the study design, collection, analysis, interpretation of data, writing, or any other type of involvement.
Supplemental Tables 1–5 and Supplemental Methods 1 and 2 are available from the “Supplementary data” link in the online posting of the article and from the same link in the online table of contents at https://academic.oup.com/ajcn/.
Copyright © 2022 American Society for Nutrition. Published by Elsevier Inc.