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Case study

Covestro’s Makrolon® and PharmaJet take the sting out of COVID-19 vaccinations

PharmaJet’s Needle-free Injection Systems (NFIS) needed a polycarbonate material that could meet the property demands of the syringe and vial adapter while standing up to gamma radiation and ethylene oxide sterilization. Makrolon® was the answer.
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Task

Create a revolutionary vaccine delivery system

PharmaJet, a leading biotech company in needle-free injection technology, set out to provide a more effective way of administering drugs and biologics. 
 
To create the components of the NFIS, PharmaJet needed a reliable polycarbonate material that could meet the demands of the application and withstand gamma radiation and ethylene oxide sterilization while being delivered consistently without supply chain headaches.
 

“We needed a polycarbonate resin that was suitable for our biotech applications and came from a vendor we could rely on. Covestro has provided great support to PharmaJet in the fight against COVID-19, allowing the collaboration to achieve better immunological results than needle and syringe delivery.”

Chris Cappello

President and CEO, PharmaJet

Pictured above is the syringe from the PharmaJet Tropis® Needle-Free Injector, which utilizes a polycarbonate resin from Covestro.
Challenge

Find a tough, reliable plastic to meet device specifications

The PharmaJet systems require a polycarbonate material to meet the specifications of the syringe and vial adapter while standing up to gamma radiation and ethylene oxide sterilization. Covestro was able to support PharmaJet’s material needs, despite supply chain issues that affected many medical suppliers. 
Solution

Makrolon®

After testing and validation, PharmaJet found Makrolon® was not only highly functional for the needle-free injection system, but that it fully withstood the high-energy radiation necessary for gamma radiation and ethylene oxide sterilization. Covestro was able to support PharmaJet’s material needs during the fight against COVID-19, despite supply chain issues that affected many medical suppliers.
 
PharmaJet’s Needle-free Injection Systems (NFIS) are being used as the method of delivery in 20+ COVID vaccine development programs and the world’s first plasmid-based DNA vaccine which recently received Emergency Use Authorization for COVID in India.
 

“Covestro is honored to provide a reliable supply of Makrolon® polycarbonate that meets the demand of needle-free injection, ultimately leading to a better patient experience, and reduced waste.”

Mark Nichols

Healthcare Key Account Manager, Covestro, LLC

Pictured above is the vial adapter from the PharmaJet Tropis® Needle-Free Injector, which utilizes a polycarbonate resin from Covestro.

Key Benefits

  • Durable Withstands gamma radiation and ethylene oxide sterilization
  • Reliable supply Covestro was able to deliver Makrolon® amid a global supply chain crisis

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Hello! Thanks for reaching out to us.
We have received your request and one of our experts will be in touch with you as soon as possible.
In the meantime, feel free to discover our innovative material solutions!

Speak to you soon,
Your Covestro Team

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