Hormone Headlines Blog

Ask the Expert: Hormone Holiday Tips

November 22, 2022

A Conversation with Nicole Ehrhardt, MD

With the holiday season in full swing, many of us find ourselves indulging in unhealthy food and drinks.  This busy time results in many people being more sedentary, and facing higher stress levels as our normal routines change. These things can often lead to an imbalanced endocrine system with symptoms like fatigue, moodiness, gastrointestinal distress, and general malaise. 

Image Melanie J. Davies, Vanita R. Aroda, Billy S. Collins, Robert A. Gabbay, Jennifer Green, Nisa M. Maruthur, Sylvia E. Rosas, Stefano Del Prato, Chantal Mathieu, Geltrude Mingrone, Peter Rossing, Tsvetalina Tankova, Apostolos Tsapas, John B. Buse; Management of Hyperglycemia in Type 2 Diabetes, 2022. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 1 November 2022; 45 (11): 2753–2786

To ensure we stay healthy and happy during the holiday period we can aim every day to work on

  • “Stepping,”
  • “Sweating,”
  • “Strengthening,” and
  • “Sleeping.”

The recent consensus report by The American Diabetes Association and the European Association for the Study of Diabetes highlight how we can best take care of our bodies throughout the year, but the challenge is finding the right balance during the holidays. 

How do diet and nutrition affect hormones? 

This is a complex question as I think we are learning more every day about hormones and their pathways. Two weight and appetite hormones are ghrelin and leptin.  We know that restricting calories increases ghrelin which can increase our appetite. Conversely, leptin reduces hunger. As you lose body weight, leptin levels become lower than ghrelin which also makes us feel hungrier. 

How do we find this balance even during the holidays? 

I think the first step is to have a plan well in advance of the holidays.  Choosing a plan that works best for you and is maintainable all year round is important.  Harvard’s public health blog is a great resource for patients and healthcare providers.  One particular blog post titled “Diet Reviews”, goes over various nutritional lifestyle plans and gives the medical evidence behind each plan.  

Two nutrition lifestyle plans that might be worth trying are intermittent fasting and the Mediterranean diet.  If you want to try intermittent fasting, you will only eat between 11 AM and 6 PM. Limiting the time period when you eat helps to avoid eating excess calories, especially if those holiday cookies are available 24-7.  If a Mediterranean lifestyle plan works for you, fill half of your plate with vegetables at your next holiday gathering and choose a small portion of lean protein.  Also, focus on eating good monounsaturated fats (such as olive oil and nuts) and only eating higher fiber foods (complex carbohydrates in smaller portion sizes). This plan might have you skipping the holiday treats altogether except on one or two “splurge” days during the holidays.  

Additionally, reading nutrition labels on foods is very important when eating out or eating on the go. When you are at the airport convenience store, grab a small bag of nuts (make sure you only eat 1 serving (150-180 calories as often there are 1.5-2 servings in a bag) rather than a bag of chips or a cookie. At the airport restaurant, be aware that the calories in the Caesar salad may be similar to a cheeseburger, Save the “splurge” for a more meaningful family gathering, and instead of either of these options, you might want to opt for a green salad with a vinaigrette.  Make sure to add protein to your salad, like grilled chicken, to help keep you full for longer.  

Pick one day to have the pumpkin spice latte or another seasonal beverage but then stick to the lower sugar options for the rest of the season.  You should enjoy the holidays but with moderation, you are going to be happier and healthier. In the short term, restricting ourselves can increase cravings but usually, cravings reduce if we can follow through with them in the long term.   

What are some tips for healthy eating during the holidays?  

I think tips 1, 2, and 3 are to try not to indulge for the entire holiday period and instead choose moderation. For example, I tell my patients living with diabetes that I do not care if their blood sugar is running in the 200 ‘s mg/dl on Thanksgiving but I hope you have a plan to give away the leftovers and that heavy carbohydrate meal after 24 hours. 

Can you keep your body in balance during this time of year? 

Image Handelsman Y, Anderson JE, Bakris GL, et al. DCRM Multispecialty Practice Recommendations for the management of diabetes, cardiorenal, and metabolic diseases. J Diabetes Complications. 2022;36(2):108101.

In addition to moderation in your diet, ensuring you get enough sleep and physical activity will help you maintain balance during the holiday.  Sleep deprivation can lead to weight gain, so it is important to practice good sleep hygiene, avoid screen time 1-2 hours before bed, avoid staying up too late and try to aim for at least 7-8 hours of sleep at night. 

In addition to getting enough sleep, I always tell my patients living with pre-diabetes and diabetes to walk for 10-15 minutes after meals since this is a natural way to bring down blood sugar and improve total steps. One of the most common things I hear is “I do not have time to exercise,” which is why we try to promote briefer but multiple daily engagements in “activity”, like walking after meals, and not formal exercise throughout the day.  

How does alcohol affect the endocrine system? What are some ways to enjoy in moderation and when should it be completely avoided? 

Drinking more than four drinks in one setting suppresses gluconeogenesis (new glucose production in the liver) by more than 40% so I always counsel patients living with diabetes about the risk for hypoglycemia when consuming alcohol. I also tell patients that have high triglycerides (>500mg/dl) to avoid alcohol given the increased risk for pancreatitis, which can be a life-threatening condition. With alcohol, moderation is key and not adding further empty calories from sugary mixed drinks is one suggestion to limit calories from alcohol. Additionally red wine increases our protective cholesterol (HDL) but it unfortunately does not decrease your bad cholesterol (LDL). HDL is also increased by exercise, so exercise may be the “better” plan for raising HDL. 

How do hormones affect mental well-being? What is the connection between hormones and emotional states? How does cold weather affect neurotransmitters? (e.g., seasonal depression) 

Serotonin is one of the most important neurotransmitters influencing mood and mental health.  As it gets colder, and darker people can develop seasonal affective disorder (SAD) and the regulation of serotonin may be part of the cause.  Also, a hormone produced in the pineal grand called melatonin is thought to be increased by shorter/darker days which causes sleepiness. 

Being active despite the darkness and cold is our natural defense against SAD. Additionally, as the risk for vitamin D deficiency increases during the winter, taking a supplement of vitamin d may also help support mood, overall health, and be good for the bones. A review and meta-analysis concluded that low levels of vitamin D are associated with depression. 

Talk to your doctor if you are feeling more down during the winter months as light therapy, psychotherapy, and medications for depression can also be used to support you. The take-home point is to let your doctor know if you have the seasonal blues. 

How can patients with diabetes prevent complications like hypoglycemia during a time with frequent routine disruptions? 

All diabetes medications have some risk for low blood sugars, but low blood sugars are much more common for those on insulin and sulfonylureas.  My tip is to try to plan in advance and keep 15 grams of carbohydrates available for when your glucose is low, or you have symptoms of low blood sugar. Additionally, if you are about to shovel snow or rush out to the store to shop for the holiday meal make sure you take the time to test your blood sugar prior to leaving. If you have insulin or sulfonylureas on board then you may want to take a small snack even if your glucose is still in the 100-110mg/dl range so that you are proactive when your glucose is in a normal range rather than reactive to a low glucose after activity . 

Is there any truth to menopausal symptoms being seasonal with an increase in severity during winter? How can patients manage hot flashes and other symptoms while still participating in holiday activities? 

A recent study showed that peaks for hot flashes and trouble sleeping occurred in July and night sweats peaked in May, while troughs occurred in January and November, respectively. However, menopausal symptoms may be more pronounced if you are experiencing seasonal affective disorder. 

Talk to your doctor if menopause symptoms are significantly affecting your quality of life. Estrogen and progesterone replacement may be appropriate especially if you are perimenopausal or recently post-menopausal, until age 60. If you have a personal risk for breast cancer or blood clot, alternative therapies could also be considered. 

Are there any research studies that have examined the effect of the holiday season on Hormone balance and if, which hormones are the main culprits during this time of year? 

I am not aware of any study on hormones specific to the holiday time but….  Often people feel more stress during the holiday season. Stress can lead to changes in the serum level of many hormones including glucocorticoids, catecholamines, growth hormone and prolactin. Moderation, planning. and asking for help is important so you can get the sleep, exercise, and relaxation you need throughout the holiday period. 

A special thank you to Laura Montour, MD for her help in developing this resource.  

a de Wiel A. Diabetes mellitus and alcohol. Diabetes Metab Res Rev. 2004 Jul-Aug;20(4):263-7.  

Anglin RE, Samaan Z, Walter SD, McDonald SD. Vitamin D deficiency and depression in adults: systematic review and meta-analysis. Br J Psychiatry. 2013 Feb;202:100-7  

Barlow SD, Elliott MR, Bondarenko I, Thurston RC, Jackson EA. Monthly variation of hot flashes, night sweats, and trouble sleeping: effect of season and proximity to the final menstrual period (FMP) in the SWAN Menstrual Calendar substudy. Menopause. 2020 Jan;27(1):5-13.  

Droste, D.W., Iliescu, C., Vaillant, M. et al. A daily glass of red wine associated with lifestyle changes independently improves blood lipids in patients with carotid arteriosclerosis: results from a randomized controlled trial. Nutr J 12, 147 (2013). 

Gupta A, Sharma PK, Garg VK, Singh AK, Mondal SC. Role of serotonin in seasonal affective disorder. Eur Rev Med Pharmacol Sci. 2013 Jan;17(1):49-55.  

Loretta DiPietro, Andrei Gribok, Michelle S. Stevens, Larry F. Hamm, William Rumpler; Three 15-min Bouts of Moderate Postmeal Walking Significantly Improves 24-h Glycemic Control in Older People at Risk for Impaired Glucose Tolerance. Diabetes Care 1 October 2013; 36 (10):  

Mehta J, Kling JM, Manson JE. Risks, Benefits, and Treatment Modalities of Menopausal Hormone Therapy: Current Concepts. Front Endocrinol (Lausanne). 2021 Mar 26;12:564781.  

Meule A. The Psychology of Food Cravings: the Role of Food Deprivation. Curr Nutr Rep. 2020 Sep;9(3):251-257  

Papatriantafyllou E, Efthymiou D, Zoumbaneas E, Popescu CA, Vassilopoulou E. Sleep Deprivation: Effects on Weight Loss and Weight Loss Maintenance. Nutrients. 2022 Apr 8;14(8):1549  

Ruiz-Ramie JJ, Barber JL, Sarzynski MA. Effects of exercise on HDL functionality. Curr Opin Lipidol. 2019 Feb;30(1):16-23 

Reynolds AN, Mann JI, Williams S, Venn BJ. Advice to walk after meals is more effective for lowering post prandial glycaemia in type 2 diabetes mellitus than advice that does not specify timing: a randomized crossover study. Diabetologia. 2016;59(12):2572-2578. 

yaribeygi H, Panahi Y, Sahraei H, Johnston TP, Sahebkar A. The impact of stress on body function: A review. EXCLI J. 2017 Jul 21;16:1057-1072 

Last Updated:
About the Expert

Nicole Ehrhardt, MD

Dr. Ehrhardt is a board-certified endocrinologist at the University of Washingon Diabetes Institute Clinic and UW assistant professor of Medicine and Metabolism, Endocrinology and Nutrition. She has served many roles in the clinical setting: hospitalist, staff endocrinologist, core faculty member of an endocrine training program, 16 years as an army doctor, and has over 10 years of experience in diabetes and obesity.
About the Expert

Nicole Ehrhardt, MD

Dr. Ehrhardt is a board-certified endocrinologist at the University of Washingon Diabetes Institute Clinic and UW assistant professor of Medicine and Metabolism, Endocrinology and Nutrition. She has served many roles in the clinical setting: hospitalist, staff endocrinologist, core faculty member of an endocrine training program, 16 years as an army doctor, and has over 10 years of experience in diabetes and obesity.

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